Previous research on European populations has studied variations in specific DNA segments and found that modern humans have inherited this DNA from Neanderthals, which is strongly associated with severe Covid-19 infections and hospitalizations. The theory suggested that the genome responsible for the serious infection of Kovid-19 was in 50 percent of South Asians and only 16 percent of Europeans.
Director, DNA Fingerprinting and Diagnostics and Chief Scientist, CSIR-Center for Cellular and Molecular Biology (CCMB), Hyderabad Kumarasami Thangaraj and Banaras Hindu University -19 will not play a role in sensitivity. These findings have been published in the journal Scientific Reports by American Nature.
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“In this study, we compared infection and case mortality with South Asian genomic data over three different timelines during an epidemic. We have paid special attention to the large population of India and Bangladesh, ”Thangaraj said.
“Our results replicate the unique genetic origins of South Asian populations and we suggest that there is a dedicated genome-wide association study on Covid-19 patients from South Asia in the Asian subcontinent,” said first author Prajjwal Pratap Singh.
“Due to the long and complex genomic history of South Asia, it is likely that we will always experience vague degrees for any disease. This study is consistent with our previous work on the ACE2 gene which showed a strong genetic correlation between case and case mortality in India compared to the presence of ACE2 gene in the Indian population, ”said Professor Chaubey of BHU.
The study also suggests that the genetic variants associated with the COVID-19 results differ significantly in the race and tribal population of Bangladesh.
“Scientists working in the field of population studies should be more careful in interpreting their findings by distinguishing between ethnic and tribal populations, more clearly in the Bangladeshi population,” said George Van Dream, the study’s translator and author. .
Director of BHU Institute Prof. “Apart from host genomics, we should also focus on what could be the way out of the host defense of people who have already been vaccinated,” said Anil K. Tripathi.
Other participants in the study include: BHU, Anshika Srivastava of Varanasi and Nargis Khanam; Abhishek Pathak and Prof. Royna Singh, Institute of Medical Sciences, BHU; Dr. G. Dr. Pankaj Srivastava from Dhaka University, Bangladesh, Forensic Science Laboratory, Sagar, MP; And Birla Institute of Scientific Research, Jaipur.